Beilstein J. Org. Chem.2021,17, 97–104, doi:10.3762/bjoc.17.10
-selectinbinders; multivalency; self-assembly in water; supramolecular polymers; Introduction
Deciphering the interaction of artificial molecular building blocks with biological components is a key element on the way to understanding and selectively manipulating biological systems. Throughout nature
of rigid supramolecular polymers. Since multivalent sulfated supramolecular structures mimic naturally occurring L-selectin ligands, the corresponding affinity was evaluated using a competitive SPR binding assay and benchmarked to an ethylene glycol-decorated supramolecular polymer.
Keywords: L
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Graphical Abstract
Scheme 1:
The synthesis of the C3-symmetrical tetraethylene glycol-decorated peptide amphiphile I and the azi...